Indicator Explainer
ESR1 Gene
This gene is involved in ligand-activated transcriptional activity.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C38349. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — ESR1 Gene (C38349)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C38349. NCI definition, reproduced without modification under CC BY 4.0.
- CLO26-113: Real-World ESR1 Gene Mutation Testing Appropriateness and Prescribing Patterns for ER-Positive HER2-Negative Advanced or Metastatic Breast Cancer. — J Natl Compr Canc Netw, 2026-03-31 (PMID 42066809; literature)
- Correspondence on "Incidence of ESR1 gene mutations among patients with endometrioid endometrial cancer" by Jang et al. — Int J Gynecol Cancer, 2026-01-15 (PMID 41611569; literature)
- Incidence of ESR1 gene mutations among patients with endometrioid endometrial cancer. — Int J Gynecol Cancer, 2025-11-21 (PMID 41435653; literature)