Indicator Explainer
CXCR4 Gene
This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C24327. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — CXCR4 Gene (C24327)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C24327. NCI definition, reproduced without modification under CC BY 4.0.
- A comparative analysis of CXCR4 gene expression from published datasets and cell surface protein levels in breast and prostate cancer models. — Biochem Biophys Res Commun, 2025-12-13 (PMID 41397322; literature)
- Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis. — Sci Rep, 2025-07-01 (PMID 40595325; literature)
- Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers. — Front Endocrinol (Lausanne), 2025-02-07 (PMID 39991734; literature)
- Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene. — PLoS One, 2024-12-23 (PMID 39715225; literature)
- Effect of SDF-1 and CXCR4 gene variants on the development of diabetic kidney disease. — Int J Med Sci, 2024-10-28 (PMID 39512693; literature)
- Association of CXCR4 gene expression and promoter methylation with chronic hepatitis B-related fibrosis/cirrhosis. — Int Immunopharmacol, 2024-07-25 (PMID 39053226; literature)