Indicator Explainer
Bone Specific Alkaline Phosphatase
An isoform of alkaline phosphatase found on the surface of osteoblasts. The level of this enzyme in a patient's serum is proportional to the amount of bone formation. This marker is used for monitoring the efficacy of both bone formation therapies and antiresorptive therapies.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C113515. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.