Test guide

TP53 Genetic Test

A TP53 genetic test uses a sample of your blood, bone marrow, or tissue from a tumor to look for changes in the tumor protein 53 gene, or TP53 for short. Changes in your genes are also called gene variants or mutations.

For everyone & professionalsReviewed 2026-10-18

What it is for

A TP53 genetic test is used to look for changes in your TP53 genes. It's not a routine test. It is often used to: Source: MedlinePlus, National Library of Medicine. Medical test information is public domain. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.

Limitations

Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.

Also known as

  • TP53 mutation analysis, TP53 full gene analysis, TP53 somatic mutation

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