Test guide

Prenatal Cell-Free DNA Screening

Prenatal cell-free DNA (cfDNA) screening is a blood test given during pregnancy . During pregnancy, some of the fetus's DNA circulates in the mother's bloodstream. A cfDNA screening checks this DNA to find out if the baby is more likely to have certain conditions caused by an abnormal number of chromosomes , such as Down syndrome .

For everyone & professionalsReviewed 2026-10-18

What it is for

A cfDNA screening is most often used to show if your unborn baby has an increased risk for one of the following chromosome disorders: The screening may also be used to: Source: MedlinePlus, National Library of Medicine. Medical test information is public domain. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.

Limitations

Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.

Also known as

  • cell-free fetal DNA, cffDNA, non-invasive prenatal tet, NIPT, non-invasive prenatal screening, NIPS

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