National Cancer Institute (source definition)
Surface Plasmon Resonance
A quantum optical-electrical phenomena consisting of an alteration in light reflectance as a result of binding of molecules to a surface from which total internal reflection is occurring. Used to detect macromolecular interactions, SPR can be used as the basis for a sensor which is capable of sensitive and quantitative measurement of a broad spectrum of chemical and biological entities.
Review and references
Automated source check (NCI definition)
2026-10-20
2026-10-20
professional use
What it is
A quantum optical-electrical phenomena consisting of an alteration in light reflectance as a result of binding of molecules to a surface from which total internal reflection is occurring. Used to detect macromolecular interactions, SPR can be used as the basis for a sensor which is capable of sensitive and quantitative measurement of a broad spectrum of chemical and biological entities.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C18117. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.