GuideDiagnostic Laboratory Methods

Laser Capture Microdissection

A high-resolution method used to isolate cells from their surrounding tissues, with the aid of a laser beam, under direct microscopic visualization. Specific cells can be isolated directly by cutting target cells away from unwanted cells, to obtain enriched cell populations.

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Updated
2026-10-18
Author
National Cancer Institute (source definition)
Reviewer
Automated source check (NCI definition)

What it is

A high-resolution method used to isolate cells from their surrounding tissues, with the aid of a laser beam, under direct microscopic visualization. Specific cells can be isolated directly by cutting target cells away from unwanted cells, to obtain enriched cell populations.

Source: National Cancer Institute, NCI Thesaurus 26.09d, C19263. NCI definition, reproduced without modification under CC BY 4.0.

Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.

Compliance note

Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.