National Cancer Institute (source definition)
Array-based Comparative Genomic Hybridization
A molecular cytogenetic method combining chromosomal comparative genomic hybridization technique and microarray to detect chromosomal aberrations and changes in DNA copy numbers in the genome, using oligonucleotides immobilized on a solid support as targets for hybridization.
Review and references
Automated source check (NCI definition)
2026-10-19
2026-10-19
professional use
References
- NCI Thesaurus 26.09d — Array-based Comparative Genomic Hybridization (C198497)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C198497. NCI definition, reproduced without modification under CC BY 4.0.
- Genomic spectrum of congenital heart disease combined with kidney and urinary tract anomalies uncovered by exome sequencing and array-CGH. — Front Cell Dev Biol, 2026-09-09 (PMID 42780563; literature)
- Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH. — Mol Cytogenet, 2025-03-28 (PMID 40155977; literature)
What it is
A molecular cytogenetic method combining chromosomal comparative genomic hybridization technique and microarray to detect chromosomal aberrations and changes in DNA copy numbers in the genome, using oligonucleotides immobilized on a solid support as targets for hybridization.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C198497. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.