Tests
Natural Killer Cells Subpopulation Count
The determination of a subpopulation of natural killer cells in a biospecimen.
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Tests
The determination of a subpopulation of natural killer cells in a biospecimen.
Indicators
A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. (NCI04)
Tests
The determination of the ratio of B-lymphocytes to leukocytes that are not T cells or natural killer cells present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of a sub-population of classical monocytes to all leukocytes that are not T-cells, B-cells, or natural killer cells, present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of the classical monocytes to all leukocytes that are not T-cells, B-cells, or natural killer cells, present in a sample. The measurement may be expressed as a ratio or percentage.
Indicators
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)
Tests
The determination of the ratio of dendritic cells to leukocytes that are not T cells, B cells or natural killer cells present in a sample. The measurement may be expressed as a ratio or percentage.
Indicators
A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
Indicators
A collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production. (NCI05)
Tests
The determination of the ratio of granulocytes to the non-classical monocytes to all leukocytes that are not T-cells, B-cells, or natural killer cells, present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of the gut-homing natural killer cells to total natural killer cells present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of gut-homing natural killer T-lymphocytes to natural killer T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.