Glossary Term
Two-Sided Test
A statistical hypothesis test that controls directional errors if rejection of a hypothesis is the result of a directional decision. The two-sided test has less statistical power than the one-sided test.
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Glossary Term
A statistical hypothesis test that controls directional errors if rejection of a hypothesis is the result of a directional decision. The two-sided test has less statistical power than the one-sided test.
Indicators
This gene is involved in RNA binding and pre-mRNA splicing.
Glossary Term
Ubiquitin is a family of widely distributed proteins found in all eukaryotes that contain a highly conserved sequence of 76 amino acids identical in organisms from humans to insects. It participates in diverse cellular functions by conjugation to other proteins through its carboxy terminus. Ubiquitination is associated with many highly regulated biological events including protein degradation, chromatin remodelling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Newly discovered families of ubiquitination and deubiquitination enzymes participate in these processes. Ubiquitination enzymes may provide new therapeutic targets and ways of intervention in many human diseases.
Partner
PathoNostics lists Ultralab E.A. Ltd in its distributor directory for Kenia.
Glossary Term
Short random nucleotide sequences that are ligated to each primer molecule during amplification of a nucleotide sample during library preparation to act as a unique tag. Their use helps to identify PCR duplicates in sequencing data.
Glossary Term
The product of so-called RNA genes; a functional RNA represents the final product of a gene rather than a transient molecule that will be translated into protein.
Tests
A uric acid test measures the amount of uric acid in a sample of your blood or urine (pee). Uric acid is a normal waste product that your body makes when it breaks down chemicals called purines. These chemicals come from your cells when they die and can be found in certain foods and beverages.
Tests
A urobilinogen in urine test measures the amount of urobilinogen in your urine (pee). Urobilinogen comes from bilirubin. Your body makes bilirubin during the normal process of breaking down old red blood cells. Your liver uses the bilirubin to make bile, a fluid that helps you digest food in your intestines. Some bile flows through your bile ducts (small tubes) from your liver directly into your intestines. The rest is stored in your gallbladder for when you need it.
Glossary Term
The act of validating; finding or testing the truth of something.
Indicators
A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis. (NCI04)
Indicators
A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.
Glossary Term
A measure of the variability in a sample or population. It is calculated as the mean squared deviation (MSD) of the individual values from their common mean. In calculating the MSD, the divisor n is commonly used for a population variance and the divisor n-1 for a sample variance.