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Indicators

Vancomycin

A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.

Tests

Vanillyl Mandelic Acid Measurement

The determination of the amount of vanillyl mandelic acid metabolite present in a sample.

For professionals

Glossary Term

Variance

A measure of the variability in a sample or population. It is calculated as the mean squared deviation (MSD) of the individual values from their common mean. In calculating the MSD, the divisor n is commonly used for a population variance and the divisor n-1 for a sample variance.

Performance Metrics

Glossary Term

Variant Allele Frequency

The relative rate of occurrence of a specific variant allele compared to the total number of alleles at that locus in the sample. This measurement may be reported as a ratio or percentage.

Pcr Terms

Glossary Term

Variation

An alteration or difference from a norm or standard.

Pcr Terms

Indicators

Vascular Endothelial Growth Factor A

Vascular endothelial growth factor A (232 aa, ~27 kDa) is encoded by the human VEGFA gene. This protein plays a role in both cell proliferation and angiogenesis.

Tests