Indicators
CHEK1 Gene
This gene is involved in the negative regulation of cell growth.
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Indicators
This gene is involved in the negative regulation of cell growth.
Indicators
This gene plays a role in cell survival and the negative regulation of cell growth.
Indicators
An animal sterol found in the body tissues (and blood plasma) of vertebrates. It can be found in large concentrations within the liver, spinal cord, and brain. Cholesterol is an important component of the membranes of cells, providing stability. It is the major precursor for the synthesis of vitamin D, of the various steroid hormones, including cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol also has an important role for the brain synapses as well as in the immune system. In conditions featuring elevated low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.
Indicators
This gene is involved in the modulation of transcription.
Indicators
A tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative. It is also used as an acidulant to control pH and acts as an anticoagulant by chelating calcium in blood.
Indicators
This gene plays a role in transcriptional regulation and in NF-kappa B signal transduction.
Indicators
This gene plays an inhibitory role in cell survival and proliferation.
Indicators
This gene is involved in signal transduction and regulation of transcription.
Indicators
This gene plays a role in protein degradation and cell cycle arrest.
Indicators
This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis.
Indicators
A non-essential sulfur-containing amino acid in humans, related to cystine, Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found in beta-keratin, the main protein in nails, skin, and hair, Cysteine is important in collagen production, as well as skin elasticity and texture. Also required in the manufacture of amino acid taurine, Cysteine is a component of the antioxidant glutathione, and plays a role in the metabolism of essential biochemicals such as coenzyme A, heparin, and biotin. (NCI04)
Indicators
This gene plays a role in signal transduction, regulation of transcription and enhancement of apoptosis.