Indicators
Coagulation Factor VII
Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.
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Indicators
Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.
Indicators
A protein complex composed of 18 complement component 1q (C1q) subcomponent chains: six C1qA, six C1qB and six C1qC. The C1q complex is part of the complement component C1 complex (C1 complex) and undergoes confirmational rearrangement following binding of pentraxins or antigen-antibody complexes that include either immunoglobulin M (IgM) or several IgG molecules. These confirmational changes activate the C1r chains of the C1 complex, which, in turn, cleaves C1s chains of the C1 complex. Following C1s cleavage, the C1 complex can proteolytically activate C2 and C4 and promotes formation of C3-convertase, which cleaves C3 and activates the classical complement pathway.
Indicators
This gene plays a role in transcriptional regulation and in NF-kappa B signal transduction.
Tests
The determination of the cross-reactive antidrug binding IgG and/or IgM antibody in a biospecimen.
Tests
The determination of the cross-reactive binding antidrug antibody in a biological sample.
Tests
The determination of the cross-reactive antidrug binding IgA antibody in a biospecimen.
Tests
The determination of the amount of cross-reactive binding antidrug IgG antibody present in a sample.
Tests
The determination of the cross-reactive antidrug binding IgG3 antibody in a biospecimen.
Indicators
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)
Article
Research record from J Virol Methods, 2026-10-21. PMID 42906759.
Indicators
This gene plays a role in DNA repair and regulation of transcription.
Tests
A proprietary enzyme-linked immunosorbent assay for semi-quantitative detection of IgG antibodies against SARS-CoV-2 using the S1 domain of the spike protein, including the receptor binding domain (RBD).