Indicators
5'-Nucleotidase
5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides.
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Indicators
5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides.
Tests
The determination of the amount of 7-alpha-hydroxy-4-cholesten-3-one in a sample.
Indicators
A family of phosphatases that add monophosphates to substrates. The optimal pH for activity of these enzymes is below 7.
Indicators
This gene is involved in signal transduction and the inhibition of apoptosis.
Indicators
The orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.
Indicators
A steroid hormone synthesized by the adrenal glands and the gonads from either 17-alpha-hydroxyprogesterone or dehydroepiandrosterone and is a precursor of testosterone.
Tests
The determination of the amount of a complex comprised of angiopoietin-related proteins 3 and 8 in a sample.
Tests
The determination of the amount of unmeasured anions (computed as sodium minus the chloride and bicarbonate) present in a sample.
Indicators
A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. (NCI04)
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Tests
A laboratory assay designed to detect elevated levels of (1,3)-beta-D-glucan in serum as an indication of infection by certain fungi species.
Glossary Term
A family of discrete probability density functions, which models systems that meet the following requirements: 1) the number of trials (n) is fixed; 2) there are only two outcomes for each trial, success or failure; 3) the outcome of each trial is independent; and 4) all trials have the same probability (p) of success. Binomial distributions show the likelihood of the number of successful trials versus the total number of trials.