Indicators
ETV6 Gene
This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
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Indicators
This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
Indicators
A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
Glossary Term
The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene.
Glossary Term
An Exonuclease is a hydrolase (nuclease) that specifically catalyzes the hydrolysis of terminal phosphodiester bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
Indicators
This gene plays a role in chromatin remodeling and transcriptional regulation.
Indicators
An abnormality that refers to mutation of factor V Leiden, which is a variant of human factor V. It results in thrombophilia, deep vein thrombosis, and a slightly increased risk of miscarriage.
Tests
The determination of the amount of the biological activity of factor X in a sample.
Glossary Term
A statistical method used for multiple testing corrections to control the expected proportion of false positives (Type I error) among rejected tests or hypotheses. It is less stringent than other multiple testing corrections and thereby, will allow a percentage of false positives.
Glossary Term
A test result that shows no evidence of a result or condition although it is present.
Glossary Term
Problem associated with the device incorrectly reporting that something has not been detected and may mislead the operator into not taking certain actions when action should be taken.
Glossary Term
A test result that shows evidence of a result or condition although it is not actually present.
Glossary Term
Problem associated with the device incorrectly reporting that something has been detected and may mislead the operator to take certain actions.