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Indicators
An amino acid derivative. Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain.
Glossary Term
A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the disease or condition. For example, one group may have been exposed to a particular substance that the other was not. Also called retrospective study.
Tests
The determination of the amount of casein present in a sample.
Indicators
This gene is involved in G-protein-coupled receptor signaling and calcium homeostasis.
Indicators
This gene plays a role in the regulation of mitotic events.
Indicators
This gene is involved in the regulation of the G1/S phase of the cell cycle.
Indicators
This gene is involved in cell cycle progression.
Tests
The determination of cellular CD152 expression in a biological specimen.
Tests
The determination of the ratio of CD161 expressing cells to total lymphocytes present in a sample. The measurement by be expressed as a ratio or percentage.
Tests
The determination of cellular CD21 expression in a biological specimen.
Indicators
This gene is involved in T cell activation and proliferation.
Indicators
A protein complex comprised of one T-cell surface glycoprotein CD3 delta chain (CD3D), one T-cell surface glycoprotein CD3 gamma chain (CD3G) and two T-cell surface glycoprotein CD3 epsilon chains (CD3E). CD3D, CD3G and CD3E are transmembrane proteins with one extracellular immunoglobulin domain and one intracellular ITAM domain. The CD3 complex is a T-cell co-receptor that noncovalently associates with either the disulfide bound heterodimeric alpha/beta T-cell receptor (TCR) or gamma/delta TCR and two copies of the accessory protein, T-cell surface glycoprotein CD3 zeta chain (CD247), which is a transmembrane protein with three ITAM domains. The TCR moiety of the TCR-CD3 complex binds to MHC and processed antigens on antigen presenting cells, which triggers phosphorylation of and cellular propagation of the signal by CD247 and the CD3 complex.
