Indicator Explainer
TP53 Gene
This gene plays a critical role in cell cycle regulation and has tumor suppressor activity.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C17359. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — TP53 Gene (C17359)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C17359. NCI definition, reproduced without modification under CC BY 4.0.
- Impact of GST and TP53 gene polymorphisms on susceptibility to end stage renal disease: A case-control analysis. — PLoS One, 2026-10-05 (PMID 42832476; literature)
- In-frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL. — J Pathol, 2026-09-24 (PMID 42786134; literature)
- Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases. — Animal Model Exp Med, 2026-08-17 (PMID 42605788; literature)