Indicator Explainer
Gamma-Glutamyl Transpeptidase
GGT participates in the transfer of amino acids across the cellular membrane and in glutathione metabolism. High concentrations are found in the liver, bile ducts, and the kidney. A test that measures the amount of GGT in the blood is used to detect diseases of the liver, bile ducts, and kidney; and to differentiate liver or bile duct (hepatobiliary) disorders from bone disease.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C37959. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Gamma-Glutamyl Transpeptidase (C37959)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C37959. NCI definition, reproduced without modification under CC BY 4.0.
- Gamma-glutamyl metformin inhibits renal cell carcinoma progression by activating AMPK signaling pathway. — Front Pharmacol, 2026-05-07 (PMID 42181886; literature)
- Preoperative gamma-glutamyl transpeptidase for predicting postoperative recurrence of hepatocellular carcinoma with wide resection margins: a multi-institutional study. — Sci Rep, 2026-04-29 (PMID 42056168; literature)
- Generation of Koku-Related Peptides Using Gamma-Glutamyl Transpeptidase Post-Treatment in Porcine Liver Hydrolyzates. — Int J Mol Sci, 2026-04-11 (PMID 42074086; literature)