Glossary Term
Repeatability and Reproducibility
Performance MetricsEN
Definition
Complementary precision measures: repeatability is variation under the same conditions (same operator, equipment, short interval); reproducibility is variation across conditions — different days, operators, lots, or laboratories.
Extended Notes
Assay verification should cover both: within-run precision across a replicate panel, and between-run variation including lot changes. Precision is concentration-dependent, so studies should include concentrations near clinical decision points, not only mid-range samples.
References
- Repeatability and reproducibility of chromatographic parameters and resulting figures of merit on polyester C-CP fiber columns for the routine isolation and analysis of HEK293-derived extracellular vesicles. — Anal Methods, 2026-09-24 (PMID 42572881; literature)
- Repeatability and Reproducibility of the Dry Eye Analyzer in Participants With and Without Symptoms of Dry Eye. — Ophthalmic Physiol Opt, 2026-09-22 (PMID 42771331; literature)
- Repeatability and reproducibility of corneal endothelial measurements using the topcon SP-1P specular microscope. — Graefes Arch Clin Exp Ophthalmol, 2026-09-04 (PMID 42696012; literature)