Glossary Term

Reading Frame

PCR TermsEN

Definition

One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in nonoverlapping triplets (codons) there are three possible ways of translating a sequence of nucleotides into a protein, each with a different starting point.

Extended Notes

Source: National Cancer Institute, NCI Thesaurus 26.09d, C63552. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.

Also Known As

FrameReading Frame
Reading Frame — IVD Glossary