Glossary Term
Mismatch Repair
PCR TermsEN
Definition
The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C20639. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Mismatch RepairMMRPost-Replication Mismatch Repair