Glossary Term
Frameshift Mutation
PCR TermsEN
Definition
A mutation occurring within the protein-coding region of a gene which results in a shift in the reading frame of the encoded protein. Frameshift mutations often result in the premature truncation of a gene product.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C17354. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
FrameshiftFrameshift MutationFrameshift Mutation AbnormalityFrameshift VariantfsMutation, FrameshiftReading Frame Shift Mutation