Glossary Term
Case-Control Study
Performance MetricsEN
Definition
A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the disease or condition. For example, one group may have been exposed to a particular substance that the other was not. Also called retrospective study.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C15197. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Case-Control Study
References
- NCI Thesaurus 26.09d — Case-Control Study (C15197)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C15197. NCI definition, reproduced without modification under CC BY 4.0.
- The emotion regulation and recognition account of empathy-related processes in autism: a multimodal, multilevel case-control study. — J Child Psychol Psychiatry, 2026-10-10 (PMID 42856069; literature)
- Nutritional Status of Patients with Hansen's Disease (Leprosy): a Case-Control Study in an Endemic Setting. — Clin Nutr ESPEN, 2026-10-09 (PMID 42854971; literature)