Glossary Term

Area Under Curve

Performance MetricsEN

Definition

The area between the x-axis and the curve given by the integrand. It is equal to the definite integral of a function. In the field of pharmacokinetics, the area under the curve (AUC) is the area under the curve in a plot of concentration of a drug in plasma against time. AUC is usually given for the time interval zero to infinity, and other time intervals are indicated.

Extended Notes

Source: National Cancer Institute, NCI Thesaurus 26.09d, C64774. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.

Also Known As

Area Under CurveAUC{AUC}