Indicators
APC Gene
This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.
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Indicators
This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.
Indicators
This gene may be involved in both transcriptional regulation and chromatin remodeling.
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This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
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This gene functions as a tumor suppressor and transcriptional regulator.
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This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.
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This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
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A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
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This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation.
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This gene plays a role in both cell cycle arrest and the inhibition of apoptosis.
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This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions.
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This gene plays a regulatory role in megakaryocytopoiesis and platelet formation.
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This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis.