Indicators
DOT1L Gene
This gene is involved in epigenetic control of gene expression.
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Indicators
This gene is involved in epigenetic control of gene expression.
Indicators
This gene is involved in chromatin structure.
Indicators
This gene is involved in chromatin structure.
Indicators
This gene is involved in histone modification.
Indicators
This gene is involved in the modulation of histone methylation.
Indicators
This gene is involved in epigenetic control of gene expression through histone methylation.
Indicators
A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis. (NCI04)