Indicators
CCND1 Gene
This gene plays a role in the regulation of mitotic events.
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Indicators
This gene plays a role in the regulation of mitotic events.
Indicators
This gene is involved in the regulation of the G1/S phase of the cell cycle.
Indicators
This gene is involved in cell cycle progression.
Indicators
This gene is involved in protein phosphorylation, RNA splicing and transcription elongation.
Indicators
This gene is involved in G1 stage cell cycle progression.
Indicators
This gene plays a role in the progression of the cell cycle.
Indicators
This gene is involved in cell cycle regulation and cyclin regulation.
Indicators
This gene functions as a tumor suppressor and transcriptional regulator.
Indicators
This gene is involved in cell cycle regulation and arrest.
Indicators
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)
Indicators
A cyclic, nonessential amino acid (actually, an imino acid) in humans (synthesized from glutamic acid and other amino acids), Proline is a constituent of many proteins. Found in high concentrations in collagen, proline constitutes almost a third of the residues. Collagen is the main supportive protein of skin, tendons, bones, and connective tissue and promotes their health and healing. (NCI04)