Article
Integrative molecular diagnostics for HPV-driven cervical carcinogenesis: a translational review of mechanisms and multimodal risk stratification.
Research record from Front Oncol, 2026-03-23. PMID 41948494.
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Article
Research record from Front Oncol, 2026-03-23. PMID 41948494.
Article
Research record from Viruses, 2026-03-27. PMID 42043206.
Indicators
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least 13 functional genes and 1 pseudogene.
Indicators
Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed of a 35-kD IL12A subunit (IL-6 Superfamily) and a 40-kDa IL12B subunit (Type I Cytokine Receptor 3 Family). IL12 stimulates T-cell-independent production of IFN-gamma by PBMCs, enhances NK cell lytic activity, acts as a growth factor for T- and NK-cells, and is important for Th1 and Th2 cell differentiation. Lymphocyte responses to IL12 require NOS2A and are mediated by STAT4 activator of transcription. (NCI)
Indicators
A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.
Tests
A measurement of a sub-population of intermediate natural killer cells present in a sample.
Glossary Term
A non-target amplification built into a reaction to prove the assay chemistry worked even when the sample is negative. It helps distinguish a true negative from inhibition or setup failure, which matters when interpreting single-target assays on difficult matrices.
Glossary Term
The difference between the 3rd and 1st quartiles is called the interquartile range and it is used as a measure of variability (dispersion).
Tests
A relative measurement (ratio or percentage) of the lymphocytes to enterocytes within the epithelium of a biological specimen.
Tests
A measurement of intramyocellular lipid normalized for tissue weight, in a sample.
Article
Research record from Methods Mol Biol, 2026-05-08. PMID 42096141.
Indicators
This gene plays a role in non-receptor tyrosine protein kinase-mediated signal transduction.