Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Indicators
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
Indicators
Neutrophil gelatinase-associated lipocalin (198 aa, ~23 kDa) is encoded by the human LCN2 gene. This protein may play a role in iron transport, apoptosis, and innate immunity.
Article
Research record from Mol Biol Rep, 2026-07-15. PMID 42455225.
Indicators
This gene plays a role in mitogenic activities affecting mesenchymal cells and is involved in receptor tyrosine kinase signal transduction.
Indicators
This gene is involved in second messenger signaling, apoptosis, cell growth and angiogenesis.
Tests
The determination of the amount of plasmin alpha-2 antiplasmin complex in a sample.
Indicators
This gene plays a role in the regulation of protein kinase A.
Tests
The determination of the amount of the prostaglandin F1 alpha in a sample.
Tests
The determination of the amount of the prostaglandin F2 alpha in a sample.
Indicators
This gene plays a role in transcription and retinoic acid receptor signal transduction.
Tests
An immunoassay that is used to determine the amount of soluble interleukin-2 receptor subunit alpha in a patient serum sample. High levels of the soluble form of the receptor can be indicative of hematological malignancies and other neoplastic disorders.
Indicators
A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.
