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Article

Targeted Hotspot Mutation Analysis of KRAS, TP53, and PTEN in Endometrial Cancer Revealed by Next-Generation Sequencing.

Research record from Curr Oncol, 2026-10-06. PMID 42930168.

Article

Targeted therapy use following Medicare's coverage expansion for next-generation sequencing in older adults with lung cancer.

Research record from JNCI Cancer Spectr, 2026-10-21. PMID 42902792.

Glossary Term

Telomere

A stretch of repetitive nucleotide sequences (TTAGGG repeats in humans) found at both ends of each chromatid arm that plays a role in chromosome stability during replication.

Pcr Terms

Indicators

TERT Gene

This gene is involved in cell cycle regulation and telomere maintenance.

Indicators

TGFBR1 Gene

This gene is involved in transcriptional regulation and cell cycle progression regulation.

Indicators

TGFBR2 Gene

This gene plays a role in cellular proliferation and mitogenic responses.

Tests

Th1-like Helper Regulatory Effector T-Lymphocyte Subpopulation to Th1-like Helper Regulatory Effector T-Lymphocyte Ratio Measurement

The determination of the ratio of a sub-population of Th1-like helper regulatory effector T-lymphocytes to total Th1-like helper regulatory effector T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.

For professionals

Article

The Clinical Utility of Droplet Digital Polymerase Chain Reaction (PCR): A Breakthrough for Cancer and Noninvasive Prenatal Genetic Disease Diagnosis.

Research record from Cureus, 2026-03-24. PMID 42037945.

Article

The Detection of BRCA1 and BRCA2 Mutations in Saudi Females with Breast Cancer in Al-Madinah Province by Next Generation Sequencing.

Research record from Clin Lab, 2026-10-01. PMID 42847947.

Article

The potential clinical benefit of routine comprehensive genomic profiling in non-small cell lung cancer for the detection of prognostic co-mutations - A multicenter next generation sequencing study.

Research record from Cancer Treat Res Commun, 2026-04-22. PMID 42172690.

Indicators

Theophylline

A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)

Glossary Term

Threshold

The lowest limit at which something becomes detectable or relevant.

Performance Metrics

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