Indicators
BARD1 Gene
This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
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Indicators
This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
Indicators
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicators
This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.
Indicators
This gene plays a role in the repression of gene transcription.
Tests
A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1. This abnormal gene is found in certain types of blood cancer , such as chronic myeloid leukemia (CML).
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Article
Research record from Cureus, 2026-08-31. PMID 42819076.
Indicators
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
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This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
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This gene plays a role in the bone morphogenetic protein signaling pathway.
Indicators
This gene is involved in cell organization/biogenesis and the inhibition of apoptosis.
Tests
A BRAF genetic test uses a sample of tumor tissue, bone marrow, or blood to look for changes in a gene called BRAF . Changes in your genes are also called gene variants or mutations. The test is usually done to look for changes in the BRAF gene that may be involved in cancer .