Glossary Term
Incidence
The relative frequency of occurrence of something.
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Glossary Term
The relative frequency of occurrence of something.
Glossary Term
A mutation class that includes insertion mutations, deletion mutations and mutation events where both an insertion and a deletion has occurred.
Tests
A measurement of the industrial mix antigen IgE antibody in a biological specimen.
Tests
The determination of the amount of the Influenza A/B antigen in a sample.
Article
Research record from JAMA Oncol, 2026-05-01. PMID 41817535.
Glossary Term
The act of hindering or obstructing or impeding.
Indicators
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least 13 functional genes and 1 pseudogene.
Indicators
Interleukin-1 beta (269 aa, ~31 kDa) is encoded by the human IL1B gene. This protein is involved in the macrophage-dependent inflammatory response.
Indicators
Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed of a 35-kD IL12A subunit (IL-6 Superfamily) and a 40-kDa IL12B subunit (Type I Cytokine Receptor 3 Family). IL12 stimulates T-cell-independent production of IFN-gamma by PBMCs, enhances NK cell lytic activity, acts as a growth factor for T- and NK-cells, and is important for Th1 and Th2 cell differentiation. Lymphocyte responses to IL12 require NOS2A and are mediated by STAT4 activator of transcription. (NCI)
Indicators
Interleukin-18 (193 aa, ~22 kDa) is encoded by the human IL18 gene. This protein is involved in the regulation of both natural killer cell activity and the production of interferon gamma.
Indicators
Interleukin-2 (153 aa, ~18 kDa) is encoded by the human IL2 gene. This protein is involved in T-cell proliferation, leukocyte stimulation and immune responses.
Indicators
A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.