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Indicators
A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.
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Interleukin-6 (212 aa, ~24 kDa) is encoded by the human IL6 gene. This protein is involved in signaling affecting a wide variety of cell types including monocytes, lymphocytes, hepatocytes and nerve cells.
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This gene plays a role in non-receptor tyrosine protein kinase-mediated signal transduction.
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This gene is involved in erythropoiesis and signal transduction.
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This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
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This gene is involved in signal transduction and apoptosis.
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This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
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This gene plays a role in both protein phosphorylation and signal transduction.
Glossary Term
The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.
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This gene plays a role in signal transduction and cytoskeletal remodeling.
Glossary Term
A reaction that contains all reagents except sample nucleic acid. Amplification in the NTC signals contamination of reagents or the environment, so NTC behavior is one of the first run-validity checks in any qPCR run log.
Glossary Term
Any part of a signal that is not the true or original signal but is introduced by the communication mechanism.
