Indicators
IKZF1 Gene
This gene is involved in B-cell and T-cell maturation.
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Indicators
This gene is involved in B-cell and T-cell maturation.
Tests
The determination of the number of the immature B2 B-lymphocytes in a sample.
Tests
The determination of the number of the memory immature B-lymphocytes in a sample.
Tests
The determination of the amount of immunoglobulin G subclass 3 present in a sample.
Tests
The determination of the amount of immunoglobulin G subclass 4 present in a sample.
Tests
The determination of the ratio of immunoglobulin G to creatinine in a biological specimen.
Tests
The determination of the amount of immunoglobulin heavy constant gamma 2 present in a sample.
Indicators
Immunoglobulin Light Chain Kappa is one of two Ig light chain types. Each Ig molecule is typically composed of two heavy chains and two light chains. Ig kappa light chains contain a variable and a constant region. Kappa light chains are encoded by multiple V, J, and C gene segments, which are separated in the genomes of cells undifferentiated with regard to antibody gene expression. Diversity in the kappa light chain V region arises during differentiation of an activated (kappa-type) antibody-producing B-cell from variable recombination of kappa V genes with kappa J genes and somatic point mutation, which plays a major role in antibody diversity. (from OMIM and NCI)
Indicators
Immunoglobulin Light Chain Lambda is one of two Ig light chain types. Each Ig molecule is typically composed of two heavy chains and two light chains but Ig lambda light chains contain a variable and a constant region. Lambda light chains are encoded by multiple V, J, and C gene segments, which are separated in the genomes of cells undifferentiated with regard to antibody gene expression. During differentiation of an activated (lambda-type) antibody-producing B-cell, diversity in the lambda light chain V region arises from variable recombination of lambda V genes with lambda J genes and somatic point mutation, which plays a major role in antibody diversity. (from OMIM 147220 and NCI)
Glossary Term
A reagent, reagent product, calibrator, control material, kit, instrument, apparatus, piece of equipment, software or system, whether used alone or in combination, intended by the manufacturer to be used in vitro for the examination of specimens, including blood and tissue donations, derived from the human body, solely or principally for the purpose of providing information to aid towards a diagnosis.
Glossary Term
The relative frequency of occurrence of something.
Glossary Term
A mutation class that includes insertion mutations, deletion mutations and mutation events where both an insertion and a deletion has occurred.