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Indicators
Antibodies in the serum of individuals with rheumatoid arthritis that react with antigenic determinants or immunoglobulins that enhance agglutination of suspended particles coated with pooled human gamma-globulin. Rheumatoid factors also occur in other autoimmune and certain infectious diseases.
Tests
A rheumatoid factor (RF) test checks a sample of your blood for rheumatoid factor, a protein made by the immune system .
Glossary Term
Single-stranded long chain of nucleotides containing ribose. It is the end product of DNA transcription by the enzyme RNA polymerase. It is essential in protein synthesis.
Glossary Term
An RNA molecule that does not contain protein-coding sequence information and constitutes the majority of the cellular RNA (~80%). This nucleic acid associates with multiple proteins to form ribosomes, which are the organelles that drive mRNA-directed protein synthesis.
Indicators
This gene plays a role in receptor tyrosine phosphorylation signal transduction, and is thought to play a role in cellular growth or differentiation, but an exact function has not been substantiated.
Tests
This test measures the amount of salicylates in the blood. Salicylates are a type of drug found in many over-the-counter and prescription medicines. These can include:
Glossary Term
Bias encountered due to enrolling study participants that do not reflect the intended target population.
Indicators
Serotransferrin (698 aa, ~77 kDa) is encoded by the human TF gene. This protein is involved in iron sequestration and transport.
Tests
An SHBG blood test measures the level of a protein called sex hormone binding globulin (SHBG) in a sample of your blood. SHBG is made mostly in your liver. It binds (attaches) to sex hormones such as testosterone and estrogen and helps control how much of these hormones are active in your body.
Article
Research record from Explor Target Antitumor Ther, 2026-09-18. PMID 42761668.
Glossary Term
A natural compound of silicon and oxygen found mostly in sand, Silica has three main crystalline varieties: quartz, tridymite, and cristobalite. Fine particulate silica dust from quartz rock causes over a long-term progressive lung injury, silicosis. (NCI04)
Article
Research record from Comb Chem High Throughput Screen, 2026-03-18. PMID 41937705.
