Indicators
BRIP1 Gene
This gene is involved in DNA double-strand break repair.
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Indicators
This gene is involved in DNA double-strand break repair.
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C peptide (31 aa, ~3 kDa) is encoded by the human INS gene. This protein is involved in both signal transduction and the modulation of blood flow.
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C-reactive protein (224 aa, ~25 kDa) is encoded by the human CRP gene. This protein is cleaved during biological activation and is associated with host defense mechanisms and inflammatory responses.
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An antigen expressed by tissues derived from mullerian epithelium (tubal, endometrial and endocervical) or celomic epithelium (mesothelial cells of the pleura, pericardium and peritoneum). Although its biochemical nature has not been clearly defined, CA125 has been described as a glycosylated, high-molecular-weight protein that may be released from damaged cells. Measurable in plasma, CA125 is a sensitive, nonspecific tumor marker for ovarian cancer; as such it is much more useful for monitoring clinical responses to the treatment of ovarian cancer than for the diagnosis of ovarian cancer. Elevated plasma CA125 may occur in association with other malignancies and non-malignant gynecologic disorders. (NCI04)
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Calcitonin (32 aa, ~3 kDa) is encoded by the human CALCA gene. This protein is involved in the modulation of blood calcium and phosphate concentrations through promoting incorporation of these ions into bone.
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A heterodimeric or heterotetrameric protein complex comprised of protein S100A8 and protein S100A9. This complex is expressed in the cytosol of neutrophils and macrophages and plays a role in multiple host defense related processes including immunomodulation, neutrophil chemotaxis and both antibacterial and antifungal responses.
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This gene plays a role in calcium binding and protein folding.
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A cancer-specific antigen associated with both tumors and the developing fetus. The main use of this antigen is as a tumor marker, especially with respect to intestinal cancers. Production of the antigen ceases shortly before birth, but may reappear in people who develop certain types of cancer.
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Proteins released into blood when heart muscle is injured; the central laboratory marker in suspected heart attack.
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This gene is involved in G-protein-coupled receptor signaling and calcium homeostasis.
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A protein complex comprised of one T-cell surface glycoprotein CD3 delta chain (CD3D), one T-cell surface glycoprotein CD3 gamma chain (CD3G) and two T-cell surface glycoprotein CD3 epsilon chains (CD3E). CD3D, CD3G and CD3E are transmembrane proteins with one extracellular immunoglobulin domain and one intracellular ITAM domain. The CD3 complex is a T-cell co-receptor that noncovalently associates with either the disulfide bound heterodimeric alpha/beta T-cell receptor (TCR) or gamma/delta TCR and two copies of the accessory protein, T-cell surface glycoprotein CD3 zeta chain (CD247), which is a transmembrane protein with three ITAM domains. The TCR moiety of the TCR-CD3 complex binds to MHC and processed antigens on antigen presenting cells, which triggers phosphorylation of and cellular propagation of the signal by CD247 and the CD3 complex.
Indicators
This gene is involved in protein phosphorylation, RNA splicing and transcription elongation.