Indicators
ATR Gene
This gene is involved in cell cycle checkpoints and DNA recombination.
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Indicators
This gene is involved in cell cycle checkpoints and DNA recombination.
Indicators
This gene plays a role in the regulation of both chromatin remodeling and transcription.
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This gene is involved in signal transduction and plays a role in development.
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This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
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This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
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This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
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This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.
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This gene plays a role in the repression of gene transcription.
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A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
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This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
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This gene plays a role in DNA unwinding and recombination-mediated telomere lengthening.
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This gene plays a role in the bone morphogenetic protein signaling pathway.