Tests
Complement C5a Measurement
The determination of the amount of complement C5a present in a sample.
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Tests
The determination of the amount of complement C5a present in a sample.
Tests
The determination of the amount of complement C5b-9 present in a sample.
Indicators
Complement component C6 (934 aa, ~105 kDa) is encoded by the human C6 gene. This protein is involved in complement-mediated host defense responses.
Indicators
Complement component C7 (843 aa, ~94 kDa) is encoded by the human C7 gene. This protein is involved in insertion of the membrane attack complex in lipid bilayers.
Indicators
A heterotrimeric protein complex composed of complement component 8 (C8) chains alpha, beta and gamma. The alpha and gamma chains form a disulfide-linked dimer that is noncovalently associated with the beta chain. C8 inserts itself into target cell membranes following formation of the C5b-6-7 complex and then recruits 10-16 molecules of C9 to complete the formation of the membrane attack complex.
Indicators
Complement component C9 (559 aa, ~63 kDa) is encoded by the human C9 gene. This protein plays a role in complement-mediated bacterial cell lysis.
Indicators
Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components.
Tests
The determination of the amount of complement factor H-related Protein 1 in a sample.
Tests
The determination of the amount of complement iC3b in a sample.
Tests
The determination of the amount of complement present in a sample.
Tests
The determination of the free complement C2 present in a sample.
Tests
The determination of the amount of free complement C5 present in a sample.