Indicators
A macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.
Tests
The determination of the number of a subpopulation of cytotoxic terminal memory T-lymphocytes in a sample.
For professionals
Tests
The determination of the ratio of a sub-population of terminal memory cytotoxic T-lymphocytes to the total terminal memory cytotoxic T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of a sub-population of cytotoxic terminal memory T-lymphocytes to a sub-population of cytotoxic terminal memory T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the ratio of the terminal memory cytotoxic T-lymphocytes to total cytotoxic T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the number of helper terminal memory T-lymphocytes in a sample.
For professionals
Tests
The determination of the number of a subpopulation of helper terminal memory T-lymphocytes in a sample.
For professionals
Tests
The determination of a sub-population of helper terminal memory T-Lymphocytes to a sub-population of helper terminal memory T-Lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the number of terminal memory T-lymphocytes in a sample.
For professionals
Tests
The determination of the ratio of a sub-population of Th1-like helper regulatory effector T-lymphocytes to total Th1-like helper regulatory effector T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the ratio of a sub-population of Th17-like helper regulatory effector T-lymphocytes to total Th17-like helper regulatory effector T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the ratio of a sub-population of Th2-like helper regulatory effector T-lymphocytes to total Th2-like helper regulatory effector T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
