Indicators
NTRK2 Gene
This gene plays a regulatory role in synaptic functions and in the long-term potentiation of brain synapses.
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Indicators
This gene plays a regulatory role in synaptic functions and in the long-term potentiation of brain synapses.
Indicators
This gene is involved in phosphoinositol signaling.
Indicators
This gene plays a role in the regulation of protein kinase A.
Indicators
A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
Indicators
This gene plays a role in chromatin remodeling and regulation of transcription.
Indicators
This gene is involved in chromatin remodeling and regulation of transcription.
Indicators
This gene plays a role in the regulation of both transcription and signaling.