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Indicators
An antinuclear antibody directed against small nuclear ribonucleoproteins (snRNPs), that is highly specific, but has poor sensitivity for systemic lupus erythematosus (SLE). Presence of anti-Sm antibodies are associated with central nervous system, kidney, lung and cardiac involvement in SLE, but are not indicative of disease activity.
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An autoantibody that reacts with cardiolipin. Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions. Some anticardiolipin antibodies prolong phospholipid dependent clotting while others are associated with spontaneous abortion.
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This gene plays a role in the transcriptional activation of androgen responsive genes.
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An essential amino acid in juvenile humans, Arginine is a complex amino acid, often found at active site in proteins and enzymes due to its amine-containing side chain. Arginine may prevent or treat heart and circulatory diseases, combat fatigue, and stimulate the immune system. It also boosts production of nitric oxide, relaxing blood vessels, and treating angina and other cardiovascular problems. Arginine is also an important intermediate in the urea cycle and in detoxification of nitrogenous wastes. (NCI04)
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This gene plays a role in transcriptional regulation.
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This gene plays a role in both chromatin remodeling and transcriptional regulation.
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This gene is involved in both transcriptional regulation and chromatin remodeling.
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This gene is involved in cell cycle checkpoints and DNA recombination.
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This gene plays a role in the regulation of both chromatin remodeling and transcription.
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This gene is involved in signal transduction and plays a role in development.
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This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
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This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
