Indicators
D-Dimer
A fibrin breakdown fragment — most useful for ruling out venous thromboembolism when clinical probability is low.
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Indicators
A fibrin breakdown fragment — most useful for ruling out venous thromboembolism when clinical probability is low.
Article
Research record from Scand J Clin Lab Invest, 2026-05-05. PMID 42085024.
Indicators
This gene plays a role in the coagulation cascade.
Tests
The determination of the ratio of the biological activity of factor XIV dependent coagulation in a subject's specimen when compared to the same activity in a control specimen. The measurement may be expressed as a ratio or percentage.
Tests
A partial thromboplastin time (PTT) test uses a blood sample to measure the number of seconds it takes for your blood to clot . Normally, when you get a cut or injury that causes bleeding, many different types of proteins in your blood work together to make a clot to stop the bleeding. These proteins are called coagulation factors or clotting factors, and your liver makes most of them.
Indicators
A measurement of the clotting time of plasma recalcified in the presence of excess tissue thromboplastin; it is a measure of the extrinsic pathway of coagulation. It is used to determine the clotting tendency of blood, in the measure of warfarin dosage, liver damage and vitamin K status. Factors measured are fibrinogen, prothrombin, and factors V, VII, and X.
Tests
A clotting test measuring the extrinsic pathway, standardised internationally as INR to monitor vitamin K antagonist therapy and assess bleeding risk.
Tests
A prothrombin time (PT) test measures how many seconds it takes for a clot to form in a blood sample. Since the results of this test can vary with different labs or test methods, your results may be used to create an INR (international normalized ratio). Using this ratio makes it easier for health care providers to compare and better understand results from different labs or test methods.
Tests
The determination of the ratio of the biological activity of reptilase dependent coagulation in a subject's specimen when compared to the same activity in a control specimen. The measurement may be expressed as a ratio or percentage.
Tests
A two-staged test with purified coagulation factors in the first stage, and a FXa-specific chromogenic substrate in the second stage. In the first stage, diluted sample plasma, which has been treated with Al(OH)3 to remove prothrombin, is mixed with a combined reagent (human serum, factor V, phospholipids and calcium). In the second stage, a subsample from the first stage is mixed with normal plasma, providing prothrombin and fibrinogen, and the clotting time is measured to deduce the amount of FVIII present.
Indicators
The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins.
Tests
The determination of the biological activity of von Willebrand coagulation factor cleaving protease, ADAMTS13, in a sample.