Indicators
Anti-Ribonucleoprotein Antibody
An antinuclear antibody directed against U1 snRNP, that is strongly associated with mixed connective tissue disease and commonly detected in lupus.
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Indicators
An antinuclear antibody directed against U1 snRNP, that is strongly associated with mixed connective tissue disease and commonly detected in lupus.
Indicators
An antinuclear antibody directed against 52 or 60 kDa RNA-binding proteins in the nucleus. They can be associated with multiple autoimmune disorders, primarily Sjogren syndrome and system lupus erythematosus. Maternal anti-Ro antibody positivity can be associated with neonatal lupus.
Tests
The determination of the amount of anti-Saccharomyces cerevisiae antibody present in a sample.
Indicators
An antinuclear antibody directed against small nuclear ribonucleoproteins (snRNPs), that is highly specific, but has poor sensitivity for systemic lupus erythematosus (SLE). Presence of anti-Sm antibodies are associated with central nervous system, kidney, lung and cardiac involvement in SLE, but are not indicative of disease activity.
Glossary Term
A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.
Tests
Antibody serology tests look for specific antibodies in your blood. Antibodies are proteins your immune system makes to fight disease-causing germs (also called pathogens), such as viruses and bacteria .
Tests
The determination of the ratio of a sub-population of antibody-secreting B-lymphocytes to antibody-secreting B-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of antibody-secreting B-lymphocytes to total class-switched memory B-lymphocyte present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the antibody-secreting B-lymphocytes in a biospecimen.
Tests
The determination of the antibody-secreting cells in a biospecimen.
Indicators
An autoantibody that reacts with cardiolipin. Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions. Some anticardiolipin antibodies prolong phospholipid dependent clotting while others are associated with spontaneous abortion.
Indicators
An autoantibody that recognizes antigens found in the cytoplasm of neutrophils.