Indicators
SDHC Gene
This gene is involved in mitochondrial electron transport.
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Indicators
This gene is involved in mitochondrial electron transport.
Indicators
A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)
Indicators
This gene may be involved in the modulation of protein SET activity.
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This gene is involved in epigenetic control of gene expression through histone methylation.
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A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
Indicators
This gene plays a role in chromatin remodeling, cell cycle control and regulation of transcription.
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This gene plays a role in chromatin remodeling and regulation of transcription.
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This gene is involved in chromatin remodeling and regulation of transcription.
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This gene plays a role in G protein-coupled receptor signal transduction and sonic hedgehog pathway activation.
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Soluble monocyte differentiation antigen CD14 is encoded by the human CD14 gene. This soluble protein may be used as a marker of monocyte activation and is derived either through cleavage that removes the glycophosphoinositol (GPI)-anchor from the membrane bound form of CD14 or as non-cleaved form secreted from the non-GPI-modified intracellular pool of CD14.
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This gene is involved in guanine nucleotide exchange.
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This gene is involved in embryonic development and in the determination of cell fate.