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Article

Clinical chemistry reference intervals in clinically validated healthy individuals: A large single-center study.

Research record from Clin Chim Acta, 2026-08-07. PMID 42567298.

Article

Clinical utility of CSF metagenomic next-generation sequencing in suspected CNS infection: performance against a composite reference standard and read-count stratification.

Research record from Front Cell Infect Microbiol, 2026-07-28. PMID 42582033.

Article

Comparative study of a reference PCR assay targeting kinetoplast DNA and a commercial kit targeting ribosomal DNA for the molecular diagnosis of visceral leishmaniasis.

Research record from J Clin Microbiol, 2026-09-25. PMID 42788736.

Article

Determination of age-specific reference intervals for ethanolamine plasmalogen species in red blood cells using liquid chromatography tandem mass spectrometry.

Research record from Clin Chim Acta, 2026-03-28. PMID 41912076.

Article

Development of Teduglutide purity certified reference material (GBW09342) through amino acid-based isotope dilution mass spectrometry and sulfur-based isotope dilution inductively coupled plasma mass spectrometry.

Research record from Talanta, 2026-06-30. PMID 42385596.

Glossary Term

Diagnostic Specificity

The probability that a test will produce a true negative result when used on non-effected subjects as compared to a reference or "gold standard". The specificity of a test can be determined by calculating: number of true negative results divided by the sum of true negative results plus number of false positive results.

Performance Metrics

Glossary Term

Digital PCR (dPCR)

A PCR format that partitions each sample into thousands of sub-reactions and calls each partition positive or negative, giving absolute quantification without a standard curve. Useful for low-level targets, copy-number work, and reference material characterization; throughput and per-test cost differ from qPCR.

Pcr Terms

Article