Indicators
Complement Component C9
Complement component C9 (559 aa, ~63 kDa) is encoded by the human C9 gene. This protein plays a role in complement-mediated bacterial cell lysis.
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Indicators
Complement component C9 (559 aa, ~63 kDa) is encoded by the human C9 gene. This protein plays a role in complement-mediated bacterial cell lysis.
Indicators
Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components.
Tests
The determination of the amount of complement factor H-related Protein 1 in a sample.
Glossary Term
A range of values for a parameter that may contain the parameter and the degree of confidence that it is in fact there.
Glossary Term
A sequence pattern derived from the alignment of multiple sequences that represents the nucleotide or amino acid most likely to occur at each position in a sequence.
Glossary Term
The presence of any substance or organism that makes a preparation impure.
Glossary Term
Variation in the number of copies of a particular sequence within the genetic material of an individual. Large-scale copy number polymorphisms are common and widely distributed in the human genome.
Glossary Term
The degree to which two or more quantities or events are linearly associated, a statistical relation between two or more variables such that systematic changes in the value of one variable are accompanied by systematic changes in the others.
Tests
The determination of the cotinine glucuronide present in a sample.
Indicators
This gene plays a role in transcriptional regulation and in NF-kappa B signal transduction.
Glossary Term
Problem associated with the degree to which an antibody or antigen participates in cross reactions.
Glossary Term
A statistical method of partitioning a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subsets are retained for subsequent use in confirming and validating the initial analysis.