Indicators
BCL2 Gene
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
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Indicators
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Tests
The determination of the number of regulatory T-lymphocytes expressing CD4, CD25 and FOXP3 present in a sample.
Indicators
This gene functions as a tumor suppressor and transcriptional regulator.
Glossary Term
A manufacturer declaration that an in vitro diagnostic complies with applicable EU legislation (the IVDR since May 2022). CE-IVD indicates regulatory conformance, not a statement of clinical superiority; buyers still review performance claims and intended use.
Article
Research record from Infect Dis Ther, 2026-04-04. PMID 41934527.
Tests
The determination of the ratio of helper regulatory effector T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of helper regulatory effector T-lymphocytes to T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Glossary Term
A WHO procedure that time-limits the listing of diagnostics (and other health products) for use in public-health emergencies when full prequalification is not yet available.
Indicators
This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.
Indicators
This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
Indicators
A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
Glossary Term
A US pathway in which a device maker demonstrates substantial equivalence to a legally marketed predicate. For IVD test kits, 510(k) clearance documents intended use and analytical/clinical support; it is distinct from CLIA waiver, which concerns point-of-care operation settings.