Indicators
A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)
Indicators
A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.
Tests
The determination of the amount of thrombospondin 1 present in a sample.
For professionals
Tests
The determination of the amount of thymidine kinase 1 in a biological sample.
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Tests
The determination of the ratio of tissue inhibitor of metalloproteinase 1 compared to creatinine present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the amount of TPR-ankyrin repeat-containing protein 1 present in a sample.
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Indicators
Transforming growth factor beta-1 (390 aa, ~44 kDa) is encoded by the human TGFB1 gene. This protein is involved in cell proliferation, cell death and a large number of signal transduction pathways.
Tests
The determination of the number of the transitional 1 B-lymphocytes in a sample.
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Tests
The determination of the amount of triggering receptor expressed on myeloid cells 1 protein in a sample.
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Tests
The determination of the amount of troponin I type 1 (slow twitch skeletal muscle) in a biological sample.
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Indicators
This gene is involved in cell cycle regulation and the loss of cellular adhesion.
Tests
A measurement of the tumor associated calcium signal transducer 2 in a sample.
For professionals