Indicators
SETD2 Gene
This gene is involved in epigenetic control of gene expression through histone methylation.
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Indicators
This gene is involved in epigenetic control of gene expression through histone methylation.
Tests
The determination of the amount of severe acute respiratory syndrome coronavirus 2 antibody in a sample.
Tests
The determination of the amount of severe acute respiratory syndrome coronavirus 2 in a sample.
Article
Research record from J Pharm Biomed Anal, 2026-06-25. PMID 42378913.
Indicators
A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
Tests
The determination of the amount of soluble interleukin 2 receptor activity present in a sample.
Indicators
This gene is involved in embryonic development and in the determination of cell fate.
Indicators
A secreted antigen derived from two nearly identical cytoplasmic glycoproteins of the serpin family, serpin B3 (SCCA-1) and serpin B4 (SCCA-2). These proteins are specifically expressed in normal squamous epithelia and are present at elevated concentrations in the serum of subjects with squamous cell carcinoma and certain inflammatory and autoimmune diseases. This antigen was first described in squamous cell cervical carcinoma; it is currently used as a nonspecific tumor marker for the presence, staging and monitoring of the disease course for squamous cell carcinomas of the head and neck, cervix, esophagus, anus and lung.
Indicators
This gene plays a role in cellular proliferation and mitogenic responses.
Indicators
A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)
Indicators
A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.
Tests
The determination of the tomoregulin-2 in a sample.